ST6GALNAC6

Across TCGA patient cohorts, ST6GALNAC6 protein abundance is significantly associated with the protein abundance of many other proteins, with 34 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ST6GALNAC6-associated proteins across cancer lineages are STK38_T282, TRIOBP_S2062, and USP33. Each is linked with ST6GALNAC6 in more than 1 cancer types. Because this analysis shows association rather than direction, both ST6GALNAC6-to-partner and partner-to-ST6GALNAC6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ST6GALNAC6 versus STK38_T282 in LSCC, with a Pearson correlation of -0.86.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ST6GALNAC6→partner) and Y-score (partner→ST6GALNAC6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	STK38_T282 →	-2.355	-3.219	.003	.006	2	1
LSCC	TRIOBP_S2062 →	+0.400	+2.890	.005	.009	2	1
LSCC	USP33 →	+0.550	+3.219	.002	.006	2	1
LSCC	YTHDC1_S146 →	-1.045	-3.219	<.001	.006	2	1
LSCC	ZNF326_S91 →	-0.904	-3.219	<.001	.006	2	1
LSCC	C10orf88 →	-0.519	-3.219	<.001	.006	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

ST6GALNAC6 vs STK38_T282 — LSCC

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