ST6GALNAC6

Across TCGA cell cohorts, ST6GALNAC6 mutation is significantly associated with the RNA expression of many other genes, with 51 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ST6GALNAC6-associated genes across cancer lineages are CLEC4C, AVP, and CCKBR. Each is linked with ST6GALNAC6 in more than 1 cancer types. Because this analysis shows association rather than direction, both ST6GALNAC6-to-partner and partner-to-ST6GALNAC6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CLEC4C grouped by ST6GALNAC6-low versus ST6GALNAC6-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ST6GALNAC6→partner) and Y-score (partner→ST6GALNAC6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	CLEC4C →	+0.022	+5.169	<.001	.005	3	1
BLOOD_Lymphoma	AVP →	+0.031	+5.209	<.001	.005	3	1
BLOOD_Leukemia	CCKBR →	+0.717	+3.864	<.001	.003	3	1
BLOOD_Leukemia	C20orf85 →	+0.027	+3.969	<.001	.009	3	1
BLOOD_Leukemia	BHLHE23 →	+1.131	+3.691	.001	.005	3	1
BLOOD_Leukemia	IL36A →	+1.104	+3.656	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 51 associations by consensus.

CLEC4C by ST6GALNAC6 expression — BREAST

Explore this box plot interactively →