Across TCGA cell cohorts, ST6GALNAC3 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible ST6GALNAC3-associated genes across cancer lineages are OR10H5, FABP12, and AADACL2. Each is linked with ST6GALNAC3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ST6GALNAC3-to-partner and partner-to-ST6GALNAC3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ST6GALNAC3→partner) and Y-score (partner→ST6GALNAC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR10H5 →	+0.028	+3.343	.004	.005	3	1
LUNG_NSCLC_LUAD	FABP12 →	+0.111	+3.215	<.001	.007	3	1
LUNG_NSCLC_LUAD	AADACL2 →	+0.026	+3.343	<.001	.005	3	1
LUNG_NSCLC_LUAD	OR2A5 →	+0.019	+3.481	<.001	.004	3	1
LUNG_NSCLC_LUAD	ZNF728 →	+0.542	+3.518	<.001	.008	3	1
SKIN	AVPR1B →	+0.009	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Exploration

ST6GALNAC3 survival (RNA) · tumor vs normal (RNA) · all ST6GALNAC3 data types