ST3GAL6

Across TCGA patient cohorts, ST3GAL6 mutation is significantly associated with the RNA expression of many other genes, with 2,902 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ST3GAL6-associated genes across cancer lineages are LINC02840, MIR4727, and SLCO1B7. Each is linked with ST3GAL6 in more than 1 cancer types. Because this analysis shows association rather than direction, both ST3GAL6-to-partner and partner-to-ST3GAL6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02840 grouped by ST3GAL6-low versus ST3GAL6-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ST3GAL6→partner) and Y-score (partner→ST3GAL6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	LINC02840 →	+0.405	+4.241	.005	.003	3	2
UCEC	MIR4727 →	+0.245	+2.464	.003	.007	3	2
UCEC	SLCO1B7 →	+0.080	+1.789	<.001	.004	3	2
UCEC	RNU6-4P →	+0.444	+2.064	.001	.001	3	2
UCEC	RNU6-39P →	+0.281	+2.077	.003	.003	3	2
UCEC	LINC01399 →	+0.225	+2.679	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,902 associations by consensus.

LINC02840 by ST3GAL6 expression — BLCA

Explore this box plot interactively →