ST3GAL5

Across TCGA patient cohorts, ST3GAL5 protein abundance is significantly associated with the RNA expression of many other genes, with 2,436 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ST3GAL5-associated genes across cancer lineages are STK32A, ST3GAL5-AS1, and SLC22A31. Each is linked with ST3GAL5 in more than 1 cancer types. Because this analysis shows association rather than direction, both ST3GAL5-to-partner and partner-to-ST3GAL5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ST3GAL5 versus STK32A in LUAD, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ST3GAL5→partner) and Y-score (partner→ST3GAL5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	STK32A →	+1.236	+0.808	<.001	<.001	3	2
LUAD	ST3GAL5-AS1 →	+1.004	+0.576	<.001	<.001	3	2
LUAD	SLC22A31 →	+1.643	+0.759	<.001	<.001	3	2
LSCC	ATAD2B →	-0.527	-0.695	.001	.009	3	2
PDAC	SERPINA4 →	-1.331	-0.538	<.001	.004	3	1
PDAC	NOMO3 →	-0.400	-0.581	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,436 associations by consensus.

ST3GAL5 vs STK32A — LUAD

Explore this scatter interactively →