ST3GAL4

Across TCGA patient cohorts, ST3GAL4 mutation is significantly associated with the RNA expression of many other genes, with 982 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ST3GAL4-associated genes across cancer lineages are CAMTA2, RAI1, and GLTP. Each is linked with ST3GAL4 in more than 1 cancer types. Because this analysis shows association rather than direction, both ST3GAL4-to-partner and partner-to-ST3GAL4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CAMTA2 grouped by ST3GAL4-low versus ST3GAL4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ST3GAL4→partner) and Y-score (partner→ST3GAL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CAMTA2 →	+0.440	+2.156	.001	.009	3	2
UCEC	RAI1 →	+0.593	+3.354	.005	.005	3	2
UCEC	GLTP →	+0.447	+2.321	.003	.006	3	2
UCEC	SLC30A5 →	+0.719	+3.523	<.001	.002	3	2
UCEC	POLR2A →	+0.610	+3.202	.008	.009	3	2
UCEC	PAX9 →	+0.979	+2.321	.003	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 982 associations by consensus.

CAMTA2 by ST3GAL4 expression — UCEC

Explore this box plot interactively →