ST20

Across TCGA patient cohorts, ST20 mutation is significantly associated with the RNA expression of many other genes, with 29 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ST20-associated genes across cancer lineages are SNRPGP7, COPS8P1, and PPIAP24. Each is linked with ST20 in more than 1 cancer types. Because this analysis shows association rather than direction, both ST20-to-partner and partner-to-ST20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNRPGP7 grouped by ST20-low versus ST20-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ST20→partner) and Y-score (partner→ST20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SNRPGP7 →	+0.633	+5.602	<.001	.004	3	2
UCEC	COPS8P1 →	+0.160	+3.748	<.001	.008	3	1
UCEC	PPIAP24 →	+0.317	+4.413	<.001	.002	3	1
COAD	MIR30B →	+0.547	+6.122	<.001	.002	3	1
COAD	MIR572 →	+0.719	+6.917	<.001	<.001	3	1
COAD	MTATP6P20 →	+0.158	+5.212	.004	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

SNRPGP7 by ST20 expression — COAD

Explore this box plot interactively →