Across TCGA patient cohorts, ST20-MTHFS RNA expression is significantly associated with the go_rna of many other GO terms, with 6,816 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible ST20-MTHFS-associated GO terms across cancer lineages are Cellular response to UV-C, Regulation of apoptotic DNA fragmentation, and Regulation of DNA catabolic process. Each is linked with ST20-MTHFS in more than 19 cancer types. Because this analysis shows association rather than direction, both ST20-MTHFS-to-partner and partner-to-ST20-MTHFS results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ST20-MTHFS→partner) and Y-score (partner→ST20-MTHFS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	Cellular response to UV-C →	+0.046	+0.508	.004	<.001	2	20
ACC	Regulation of apoptotic DNA fragmentation →	+0.037	+0.387	.001	.001	3	14
UVM	Regulation of DNA catabolic process →	+0.037	+0.371	<.001	<.001	2	13
THYM	Regulation of DNA-templated DNA replication →	+0.042	+0.143	<.001	.004	2	12
UVM	DNA-templated DNA replication →	+0.031	+0.385	<.001	<.001	3	11
MESO	Cytoplasmic sequestering of NF-kappaB →	+0.053	+0.355	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,816 associations by consensus.

Exploration

ST20-MTHFS survival (RNA) · tumor vs normal (RNA) · all ST20-MTHFS data types