ST14

Across TCGA cell cohorts, ST14 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,323 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ST14-associated GO terms across cancer lineages are Serotonin secretion, Serotonin production involved in inflammatory response, and Serotonin secretion involved in inflammatory response. Each is linked with ST14 in more than 12 cancer types. Because this analysis shows association rather than direction, both ST14-to-partner and partner-to-ST14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Serotonin secretion grouped by ST14-low versus ST14-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ST14→partner) and Y-score (partner→ST14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Serotonin secretion →	+1.577	+4.639	<.001	<.001	3	13
LUNG_NSCLC_LUSC	Serotonin production involved in inflammatory response →	+1.577	+4.639	<.001	<.001	3	13
LUNG_NSCLC_LUSC	Serotonin secretion involved in inflammatory response →	+1.577	+4.639	<.001	<.001	3	13
BLOOD_Lymphoma	Response to molecule of fungal origin →	+1.718	+3.207	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Regulation of neutrophil degranulation →	+1.541	+4.994	.005	<.001	3	12
BLOOD_Lymphoma	Cellular response to molecule of fungal origin →	+1.718	+3.207	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,323 associations by consensus.

Serotonin secretion by ST14 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →