SSX6P

Across TCGA patient cohorts, SSX6P mutation is significantly associated with the RNA expression of many other genes, with 2,295 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SSX6P-associated genes across cancer lineages are SEC13, DBF4B, and NOL9. Each is linked with SSX6P in more than 1 cancer types. Because this analysis shows association rather than direction, both SSX6P-to-partner and partner-to-SSX6P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SEC13 grouped by SSX6P-low versus SSX6P-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SSX6P→partner) and Y-score (partner→SSX6P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SEC13 →	+0.321	+2.000	.005	.003	3	2
UCEC	DBF4B →	+0.546	+2.458	<.001	.001	3	2
UCEC	NOL9 →	+0.436	+2.445	.001	<.001	3	2
UCEC	CDC25A →	+0.611	+2.000	.001	.003	3	2
UCEC	POC1A →	+0.496	+2.431	.008	.001	3	2
UCEC	MAP2K1 →	+0.534	+2.032	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,295 associations by consensus.

SEC13 by SSX6P expression — UCEC

Explore this box plot interactively →