SSX6P

Across TCGA pan-cancer cohorts, SSX6P RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of SSX6P’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where SSX6P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SSX6P is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.

HNSC, ESCA, and KIRC are the cancer types where SSX6P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SSX6P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	II,III,IV	+0.166	.004	6	view →
ESCA	All	II,III,IV	+0.035	.019	2	view →
KIRC	Female	II,III,IV	−0.023	.031	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

SSX6P–HNSC

Open the HNSC breakdown →