SSX6P

Across TCGA patient cohorts, SSX6P mutation is significantly associated with the total protein of many other genes, with 52 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SSX6P-associated genes across cancer lineages are Mre11, JNK2, and CD49b. Each is linked with SSX6P in more than 1 cancer types. Because this analysis shows association rather than direction, both SSX6P-to-partner and partner-to-SSX6P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mre11 grouped by SSX6P-low versus SSX6P-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SSX6P→partner) and Y-score (partner→SSX6P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Mre11 →	-0.188	-3.000	.024	.036	3	2
UCEC	JNK2 →	+0.204	+1.901	.006	.028	3	2
UCEC	CD49b →	-0.232	-1.680	.030	.042	3	2
SKCM	FOXO3a →	-0.135	-3.000	.041	.036	3	1
SKCM	Bad_pS112 →	+0.256	+3.000	.015	.036	3	1
UCEC	14-3-3_beta →	-0.098	-2.558	.009	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 52 associations by consensus.

Mre11 by SSX6P expression — SKCM

Explore this box plot interactively →