SSX4B

Across TCGA patient cohorts, SSX4B RNA expression is significantly associated with the go_rna of many other GO terms, with 2,728 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SSX4B-associated GO terms across cancer lineages are Mitotic metaphase chromosome alignment, Negative regulation of chromosome organization, and Metaphase chromosome alignment. Each is linked with SSX4B in more than 6 cancer types. Because this analysis shows association rather than direction, both SSX4B-to-partner and partner-to-SSX4B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic metaphase chromosome alignment grouped by SSX4B-low versus SSX4B-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SSX4B→partner) and Y-score (partner→SSX4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Mitotic metaphase chromosome alignment →	+0.062	+0.067	<.001	.001	3	7
STAD	Negative regulation of chromosome organization →	+0.055	+0.076	<.001	<.001	3	5
STAD	Metaphase chromosome alignment →	+0.062	+0.070	<.001	.001	3	5
STAD	DNA conformation change →	+0.053	+0.071	<.001	.001	3	5
STAD	Regulation of spindle organization →	+0.047	+0.063	<.001	.003	3	5
STAD	Regulation of cyclin-dependent protein kinase activity →	+0.047	+0.086	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,728 associations by consensus.

Mitotic metaphase chromosome alignment by SSX4B expression — STAD

Explore this box plot interactively →