Across TCGA pan-cancer cohorts, SSX4B RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of SSX4B’s most consistent transcriptional readouts.
The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where SSX4B RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SSX4B is over-expressed in tumor.
LIHC are the cancer types where SSX4B tumor–normal differential expression is most reproducible.