SSU72

Across TCGA patient cohorts, SSU72 mutation is significantly associated with the RNA expression of many other genes, with 348 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SSU72-associated genes across cancer lineages are RNA5SP502, LINC00459, and LINC01518. Each is linked with SSU72 in more than 1 cancer types. Because this analysis shows association rather than direction, both SSU72-to-partner and partner-to-SSU72 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP502 grouped by SSU72-low versus SSU72-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SSU72→partner) and Y-score (partner→SSU72) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNA5SP502 →	+0.360	+5.411	<.001	.005	3	2
UCEC	LINC00459 →	+0.136	+3.274	.001	.001	3	2
UCEC	LINC01518 →	+1.010	+3.072	.008	.002	3	2
SKCM	MIR30E →	+0.324	+4.743	<.001	.005	3	2
SKCM	RNU6-22P →	+0.396	+3.913	<.001	.006	3	2
SKCM	MIR542 →	+0.218	+4.884	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 348 associations by consensus.

RNA5SP502 by SSU72 expression — BLCA

Explore this box plot interactively →