SSU72

Across TCGA pan-cancer cohorts, SSU72 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated SSU72 data layer compared with 3 for mutation status and 4 for mass-spec protein.

The strongest signal is observed in kidney chromophobe (KICH), where higher SSU72 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SSU72 expression acts as an unfavorable survival marker, although some lineages such as CHOL and KIRC show a favorable association.

KICH, ACC, and LGG are the cancer types where SSU72 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Median	III,IV	0.065	1.000	<.001	89	view →
ACC	OS	Tertile	All	0.731	0.954	<.001	81	view →
LGG	DFS	Median	All	0.633	0.844	<.001	50	view →
UCEC	DFS	Tertile	IV	0.175	0.747	<.001	46	view →
LIHC	OS	Median	All	0.716	0.831	.001	36	view →
SKCM	OS	Median	III,IV	0.625	0.778	.002	32	view →
BLCA	OS	Tertile	All	0.555	0.688	.009	30	view →
CHOL	DFS	Median	All	0.710	0.242	.005	27	view →
KIRC	DFS	Tertile	All	0.816	0.458	<.001	24	view →
COAD	OS	Median	IV	0.266	0.842	.003	20	view →
THYM	OS	Median	All	1.000	0.779	.004	16	view →
LUSC	DFS	Quartile	III,IV	0.225	0.575	.011	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

SSU72–KICH (DFS)

Open the KICH breakdown →