Q-omics provides the consensus-scored MIR542 profile across patient tissues and cancer cell-line models. MIR542 expression is associated with patient survival in 13 of 34 cancer types, with the highest sampling consensus in ACC. Among the 18 cancer types available for tumor–normal comparison, MIR542 is differentially expressed in 3, with the highest sampling consensus in UCEC. Additionally, MIR542 RNA expression shows 6,053 significant gene co-expression associations, with the highest sampling consensus in UCEC. Together, these results highlight ACC, and UCEC as cancer lineages where MIR542 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MIR542 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MIR542 survival associations across molecular data types. MIR542 RNA expression shows survival associations in the most cancer types (13), followed by mutation status (1). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MIR542 RNA expression–survival associations across cancer types. High MIR542 expression shows unfavorable associations in ACC, MESO, LUSC, COAD, UCEC and LUAD. The ACC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify ACC as the clearest survival context for MIR542 RNA expression.
This table summarizes MIR542 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 3. The strongest signals are observed in UCEC for RNA.
This table ranks reproducible tumor–normal expression differences for MIR542. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MIR542 shows lower tumor expression in UCEC and KIRC and higher tumor expression in THCA. The UCEC box plot shows higher MIR542 RNA expression in normal versus tumor tissue (log2 FC = −0.264, t-test p = .024).
This table shows molecular features associated with MIR542 in patient tissues and cancer cell lines. In patient samples, MIR542 shows the broadest associations at the RNA and protein expression levels, with UCEC recurring as the lineage with the largest associated feature set.
