Across TCGA patient cohorts, MIR542 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MIR542-associated genes across cancer lineages are MIR8064, RNU6-13P, and MIR181B1. Each is linked with MIR542 in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR542-to-partner and partner-to-MIR542 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR542→partner) and Y-score (partner→MIR542) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR8064 →	+0.954	+4.633	<.001	.004	3	1
UCEC	RNU6-13P →	+0.550	+4.969	.001	.002	3	1
UCEC	MIR181B1 →	+0.749	+5.666	<.001	<.001	3	1
UCEC	BMS1P11 →	+0.135	+4.606	.002	.004	3	1
UCEC	NLGN4Y-AS1 →	+0.124	+4.937	<.001	.005	3	1
UCEC	RPL12P43 →	+0.250	+4.448	.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Exploration

MIR542 survival (RNA) · tumor vs normal (RNA) · all MIR542 data types