SSTR4

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SSTR4 mutation is significantly associated with the RNA expression of many other genes, with 1,699 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SSTR4-associated genes across cancer lineages are RN7SL97P, RNU6-497P, and RNU2-32P. Each is linked with SSTR4 in more than 3 cancer types. Because this analysis shows association rather than direction, both SSTR4-to-partner and partner-to-SSTR4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL97P grouped by SSTR4-low versus SSTR4-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SSTR4→partner) and Y-score (partner→SSTR4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCRN7SL97P →+0.189+5.144<.001.00334
LIHCRNU6-497P →+0.292+5.758.009.00333
CESCRNU2-32P →+0.648+4.276<.001.00833
UCECRN7SL248P →+0.046+2.783<.001.00932
LIHCMT-TN →+1.052+5.033<.001.00932
LIHCACTG1P18 →+0.042+5.033<.001.00932
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,699 associations by consensus.

RN7SL97P by SSTR4 expression — CESC

Box plot of RN7SL97P in SSTR4-low vs SSTR4-high samples in CESC.

Explore this box plot interactively →

Exploration