SSB

Across TCGA cell cohorts, SSB RNA expression is significantly associated with the go_rna of many other GO terms, with 4,703 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible SSB-associated GO terms across cancer lineages are Nuclear pore organization, Mitochondrial tRNA processing, and Mitotic sister chromatid cohesion. Each is linked with SSB in more than 16 cancer types. Because this analysis shows association rather than direction, both SSB-to-partner and partner-to-SSB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear pore organization grouped by SSB-low versus SSB-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SSB→partner) and Y-score (partner→SSB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Nuclear pore organization →	+0.134	+0.622	<.001	.001	3	17
BONE	Mitochondrial tRNA processing →	+0.097	+0.519	.001	<.001	3	17
OVARY	Mitotic sister chromatid cohesion →	+0.142	+0.904	<.001	<.001	3	16
BONE	Mitochondrial RNA metabolic process →	+0.097	+0.727	.007	<.001	3	16
BONE	Mitochondrial RNA processing →	+0.120	+0.559	<.001	<.001	3	16
BONE	Maturation of SSU-rRNA →	+0.162	+0.625	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,703 associations by consensus.

Nuclear pore organization by SSB expression — KIDNEY

Explore this box plot interactively →