SRRT

Across TCGA cell cohorts, SRRT RNA expression is significantly associated with the go_rna of many other GO terms, with 4,987 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SRRT-associated GO terms across cancer lineages are Leading strand elongation, Regulation of DNA-templated DNA replication, and Cell cycle DNA replication. Each is linked with SRRT in more than 19 cancer types. Because this analysis shows association rather than direction, both SRRT-to-partner and partner-to-SRRT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Leading strand elongation grouped by SRRT-low versus SRRT-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SRRT→partner) and Y-score (partner→SRRT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Leading strand elongation →	+0.200	+0.902	<.001	.006	3	20
PANCREAS	Regulation of DNA-templated DNA replication →	+0.129	+0.910	<.001	<.001	3	20
BONE	Cell cycle DNA replication →	+0.156	+0.812	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	DNA-templated DNA replication maintenance of fidelity →	+0.119	+1.381	<.001	<.001	3	19
PANCREAS	Mitotic chromosome condensation →	+0.162	+0.667	<.001	.002	3	19
BONE	DNA replication checkpoint signaling →	+0.181	+0.942	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,987 associations by consensus.

Leading strand elongation by SRRT expression — LIVER

Explore this box plot interactively →