SRP68P3

Across TCGA patient cohorts, SRP68P3 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible SRP68P3-associated genes across cancer lineages are MOS, MTCO3P4, and SEPTIN14P24. Each is linked with SRP68P3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SRP68P3-to-partner and partner-to-SRP68P3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MOS grouped by SRP68P3-low versus SRP68P3-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SRP68P3→partner) and Y-score (partner→SRP68P3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MOS →	+0.488	+5.157	<.001	.007	3	1
LUAD	MTCO3P4 →	+0.089	+5.888	<.001	.002	3	1
LUAD	SEPTIN14P24 →	+0.472	+5.343	<.001	.006	3	1
LUAD	IFNA13 →	+0.048	+6.315	<.001	.001	3	1
LUAD	LINC01241 →	+0.064	+5.099	<.001	.008	3	1
LUAD	RN7SL790P →	+0.318	+5.044	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

MOS by SRP68P3 expression — LUAD

Explore this box plot interactively →