SRP68P3

Across TCGA pan-cancer cohorts, SRP68P3 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated SRP68P3 data layer.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher SRP68P3 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SRP68P3 expression acts as an unfavorable survival marker, although some lineages such as LUAD and PRAD show a favorable association.

CESC, CHOL, and LUSC are the cancer types where SRP68P3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	DFS	Tertile	All	0.386	0.582	<.001	36	view →
CHOL	OS	Tertile	III,IV	0.162	0.915	.004	36	view →
LUSC	DFS	Tertile	III,IV	0.161	0.693	.003	32	view →
READ	DFS	Tertile	IV	0.027	0.636	<.001	30	view →
DLBC	OS	Tertile	III,IV	0.172	1.000	.014	26	view →
UVM	OS	Tertile	All	0.519	0.811	.019	12	view →
KIRP	DFS	Tertile	All	0.766	0.886	.029	12	view →
MESO	OS	Quartile	All	0.143	0.573	.001	9	view →
LIHC	DFS	Tertile	All	0.121	0.534	.002	9	view →
KIRC	DFS	Tertile	III,IV	0.635	0.797	.017	8	view →
OV	OS	Quartile	II,III,IV	0.798	0.855	.032	8	view →
LUAD	OS	Tertile	III,IV	0.627	0.442	.036	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

SRP68P3–CESC (DFS)

Open the CESC breakdown →