SRI-AS1

Across TCGA patient cohorts, SRI-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,801 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SRI-AS1-associated proteins across cancer lineages are SRI, ZNF48_S416, and ZNF768_S83. Each is linked with SRI-AS1 in more than 6 cancer types. Because this analysis shows association rather than direction, both SRI-AS1-to-partner and partner-to-SRI-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SRI-AS1 versus SRI in PDAC, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SRI-AS1→partner) and Y-score (partner→SRI-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	SRI →	+0.468	+0.451	<.001	.001	3	7
LSCC	ZNF48_S416 →	+0.417	+0.607	<.001	.001	3	3
HNSC	ZNF768_S83 →	+0.607	+0.744	<.001	<.001	3	3
GBM	CRELD2 →	-0.505	-0.373	<.001	.004	3	3
CCRCC	GAB2_S543 →	+0.766	+0.460	.001	<.001	3	3
HNSC	FAM110C_S241 →	-0.845	-0.692	.009	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,801 associations by consensus.

SRI-AS1 vs SRI — PDAC

Explore this scatter interactively →