SPTY2D1OS

Across TCGA patient cohorts, SPTY2D1OS mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SPTY2D1OS-associated genes across cancer lineages are RNU6-891P, RNU6-1026P, and CDKN2AIPNLP3. Each is linked with SPTY2D1OS in more than 1 cancer types. Because this analysis shows association rather than direction, both SPTY2D1OS-to-partner and partner-to-SPTY2D1OS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-891P grouped by SPTY2D1OS-low versus SPTY2D1OS-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPTY2D1OS→partner) and Y-score (partner→SPTY2D1OS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-891P →	+0.617	+4.778	<.001	.003	3	1
UCEC	RNU6-1026P →	+0.544	+4.937	<.001	.005	3	1
UCEC	CDKN2AIPNLP3 →	+0.200	+4.852	<.001	.006	3	1
UCEC	ATG3P1 →	+0.134	+5.123	<.001	.004	3	1
UCEC	HMGB3P1 →	+0.196	+4.499	<.001	.005	3	1
UCEC	ELOCP24 →	+0.245	+5.453	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

RNU6-891P by SPTY2D1OS expression — UCEC

Explore this box plot interactively →