SPTY2D1

Across TCGA patient cohorts, SPTY2D1 mutation is significantly associated with the RNA expression of many other genes, with 3,110 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SPTY2D1-associated genes across cancer lineages are ANKRD20A6P, SNORD127, and ADAD1. Each is linked with SPTY2D1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SPTY2D1-to-partner and partner-to-SPTY2D1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ANKRD20A6P grouped by SPTY2D1-low versus SPTY2D1-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPTY2D1→partner) and Y-score (partner→SPTY2D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	ANKRD20A6P →	+0.224	+4.341	<.001	.007	3	3
COAD	SNORD127 →	+0.918	+3.015	<.001	.005	3	3
BRCA	ADAD1 →	+0.163	+3.264	<.001	.009	3	3
UCEC	THAP3 →	+0.252	+1.839	.001	.002	3	3
UCEC	PSMB6 →	+0.349	+1.941	<.001	<.001	3	3
BLCA	OR7E31P →	+0.073	+3.423	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,110 associations by consensus.

ANKRD20A6P by SPTY2D1 expression — READ

Explore this box plot interactively →