SPTBN5

Across TCGA patient cohorts, SPTBN5 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,460 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible SPTBN5-associated proteins across cancer lineages are MON1B, ARCN1, and COPB1. Each is linked with SPTBN5 in more than 2 cancer types. Because this analysis shows association rather than direction, both SPTBN5-to-partner and partner-to-SPTBN5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPTBN5 versus MON1B in CCRCC, with a Pearson correlation of -0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPTBN5→partner) and Y-score (partner→SPTBN5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	MON1B →	-0.242	-0.480	<.001	<.001	3	3
LSCC	ARCN1 →	-0.192	-0.566	.001	.002	3	3
CCRCC	COPB1 →	-0.182	-0.461	<.001	<.001	3	3
LSCC	KRT80 →	+0.677	+0.440	.005	.001	3	3
LUAD	RHEB →	+0.357	+0.475	<.001	<.001	3	3
LSCC	RRBP1 →	-0.417	-0.585	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,460 associations by consensus.

SPTBN5 vs MON1B — CCRCC

Explore this scatter interactively →