SPRY4-AS1

Across TCGA patient cohorts, SPRY4-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,602 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible SPRY4-AS1-associated proteins across cancer lineages are SPRY4, SPRY4_S280, and CSTA. Each is linked with SPRY4-AS1 in more than 4 cancer types. Because this analysis shows association rather than direction, both SPRY4-AS1-to-partner and partner-to-SPRY4-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPRY4-AS1 versus SPRY4 in OV, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPRY4-AS1→partner) and Y-score (partner→SPRY4-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SPRY4 →	+0.858	+0.582	<.001	<.001	3	5
LUAD	SPRY4_S280 →	+1.330	+1.085	<.001	<.001	3	5
HNSC	CSTA →	-0.957	-0.637	<.001	<.001	3	5
LUAD	IRF2BPL →	+0.317	+0.657	<.001	<.001	3	5
GBM	ARAP3 →	+0.704	+0.873	<.001	<.001	3	4
PDAC	NT5E →	+0.565	+0.358	<.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,602 associations by consensus.

SPRY4-AS1 vs SPRY4 — OV

Explore this scatter interactively →