Across TCGA patient cohorts, SPRR2C mutation is significantly associated with the RNA expression of many other genes, with 27 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SPRR2C-associated genes across cancer lineages are RN7SL201P, TAB3P1, and RN7SL382P. Each is linked with SPRR2C in more than 1 cancer types. Because this analysis shows association rather than direction, both SPRR2C-to-partner and partner-to-SPRR2C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPRR2C→partner) and Y-score (partner→SPRR2C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SL201P →	+0.308	+5.877	<.001	<.001	3	2
SKCM	TAB3P1 →	+0.072	+4.875	<.001	.002	3	1
SKCM	RN7SL382P →	+0.178	+4.241	.001	.008	3	1
SKCM	LINC02220 →	+0.818	+4.730	<.001	.003	3	1
LUAD	RNU6-1040P →	+0.497	+7.930	<.001	.008	3	1
LUAD	MIR515-2 →	+0.958	+7.930	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

Exploration

SPRR2C survival (RNA) · tumor vs normal (RNA) · all SPRR2C data types