SPRR2B

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SPRR2B RNA expression is significantly associated with the go_rna of many other GO terms, with 6,363 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible SPRR2B-associated GO terms across cancer lineages are Keratinization, Autocrine signaling, and Intermediate filament-based process. Each is linked with SPRR2B in more than 11 cancer types. Because this analysis shows association rather than direction, both SPRR2B-to-partner and partner-to-SPRR2B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPRR2B→partner) and Y-score (partner→SPRR2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
ESCAKeratinization →+0.270+3.928<.001<.001312
ESCAAutocrine signaling →+0.162+3.336<.001<.00139
ESCAIntermediate filament-based process →+0.073+2.254<.001<.00139
ESCAIntermediate filament organization →+0.124+3.112<.001<.00139
ESCAAmmonium homeostasis →+0.598+3.662<.001<.00138
HNSCAntimicrobial peptide production →+0.181+3.911<.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,363 associations by consensus.

Exploration