SPRR2B

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SPRR2B mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SPRR2B-associated genes across cancer lineages are Neutrophils and Macrophages M2. Each is linked with SPRR2B in more than 1 cancer types. Because this analysis shows association rather than direction, both SPRR2B-to-partner and partner-to-SPRR2B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPRR2B→partner) and Y-score (partner→SPRR2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADNeutrophils →+0.006+3.197.036.04832
SKCMMacrophages M2 →-0.021-2.389.029.02111
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Exploration