Across TCGA cell cohorts, SPRR2B RNA expression is significantly associated with the drug of many other genes, with 97 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SPRR2B-associated genes across cancer lineages are IAP_7638, Dasatinib, and AZD5363. Each is linked with SPRR2B in more than 3 cancer types. Because this analysis shows association rather than direction, both SPRR2B-to-partner and partner-to-SPRR2B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPRR2B→partner) and Y-score (partner→SPRR2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	IAP_7638 →	+1.446	+0.031	<.001	.033	3	4
SKIN	Dasatinib →	+1.465	+0.042	<.001	.034	3	3
SKIN	AZD5363 →	+0.585	+0.031	.048	.041	3	3
LUNG_NSCLC_LUAD	AZD6738 →	+0.668	+0.009	.027	.040	3	3
SKIN	Camptothecin →	+0.628	+0.044	.018	.041	3	2
LUNG_NSCLC_LUAD	Docetaxel →	+0.956	+0.009	.018	.040	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 97 associations by consensus.

Exploration

SPRR2B survival (RNA) · tumor vs normal (RNA) · all SPRR2B data types