SPON1-AS1

Across TCGA patient cohorts, SPON1-AS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,088 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SPON1-AS1-associated GO terms across cancer lineages are Regulation of telomere maintenance via telomere lengthening, Peptidyl-lysine modification, and Nuclear-transcribed mRNA poly(A) tail shortening. Each is linked with SPON1-AS1 in more than 23 cancer types. Because this analysis shows association rather than direction, both SPON1-AS1-to-partner and partner-to-SPON1-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of telomere maintenance via telomere lengthening grouped by SPON1-AS1-low versus SPON1-AS1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPON1-AS1→partner) and Y-score (partner→SPON1-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Regulation of telomere maintenance via telomere lengthening →	+0.046	+0.236	<.001	.003	3	23
STAD	Peptidyl-lysine modification →	+0.044	+0.469	<.001	<.001	3	22
STAD	Nuclear-transcribed mRNA poly(A) tail shortening →	+0.062	+0.541	<.001	<.001	3	22
ESCA	Regulation of telomere maintenance →	+0.045	+0.266	<.001	<.001	3	22
STAD	Regulation of post-translational protein modification →	+0.046	+0.380	<.001	<.001	3	22
ESCA	Telomere maintenance →	+0.042	+0.235	.001	.004	1	24

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,088 associations by consensus.

Regulation of telomere maintenance via telomere lengthening by SPON1-AS1 expression — ESCA

Explore this box plot interactively →