SPINK2

Across TCGA patient cohorts, SPINK2 RNA expression is significantly associated with the RNA expression of many other genes, with 15,223 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible SPINK2-associated genes across cancer lineages are HOPX, SELENOM, and GNG8. Each is linked with SPINK2 in more than 19 cancer types. Because this analysis shows association rather than direction, both SPINK2-to-partner and partner-to-SPINK2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPINK2 versus HOPX in DLBC, with a Pearson correlation of 0.75.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPINK2→partner) and Y-score (partner→SPINK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	HOPX →	+2.283	+2.996	<.001	<.001	3	20
KIRP	SELENOM →	+1.292	+0.454	<.001	<.001	3	19
DLBC	GNG8 →	+3.476	+3.091	<.001	<.001	3	18
LAML	LINC00173 →	+1.323	+2.214	<.001	<.001	3	16
STAD	VPREB3 →	+1.714	+0.377	<.001	<.001	3	16
SARC	CA11 →	+1.007	+0.599	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,223 associations by consensus.

SPINK2 vs HOPX — DLBC

Explore this scatter interactively →