Across TCGA patient cohorts, SPIN4 mutation is significantly associated with the RNA expression of many other genes, with 2,784 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SPIN4-associated genes across cancer lineages are RN7SL134P, MIR6803, and LINC01072. Each is linked with SPIN4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SPIN4-to-partner and partner-to-SPIN4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPIN4→partner) and Y-score (partner→SPIN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RN7SL134P →	+0.208	+4.874	<.001	.002	3	2
UCEC	MIR6803 →	+0.094	+3.723	<.001	.008	3	2
CESC	LINC01072 →	+0.246	+5.345	<.001	.001	3	1
CESC	LINC02559 →	+1.329	+5.342	<.001	.002	3	1
CESC	OR5G3 →	+0.098	+4.934	<.001	.002	3	1
CESC	FAM8A2P →	+0.041	+4.539	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,784 associations by consensus.

Exploration

SPIN4 survival (RNA) · tumor vs normal (RNA) · all SPIN4 data types