Across TCGA patient cohorts, SPIN3 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,542 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SPIN3-associated proteins across cancer lineages are HUWE1, CKAP4_S26, and HNRNPU. Each is linked with SPIN3 in more than 6 cancer types. Because this analysis shows association rather than direction, both SPIN3-to-partner and partner-to-SPIN3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPIN3→partner) and Y-score (partner→SPIN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	HUWE1 →	+0.239	+0.787	<.001	<.001	3	7
BRCA	CKAP4_S26 →	-0.654	-0.448	.004	.002	3	6
GBM	HNRNPU →	+0.280	+0.569	<.001	<.001	3	6
BRCA	TCEAL1 →	+0.525	+0.443	<.001	<.001	3	6
GBM	STAG2 →	+0.289	+0.521	<.001	<.001	3	6
COAD	UBA2 →	+0.392	+1.066	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,542 associations by consensus.

Exploration

SPIN3 survival (RNA) · tumor vs normal (RNA) · all SPIN3 data types