SPIN3

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SPIN3 protein abundance is significantly associated with the RNA expression of many other genes, with 9,592 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SPIN3-associated genes across cancer lineages are EFS, BCHE, and AKT3. Each is linked with SPIN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SPIN3-to-partner and partner-to-SPIN3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPIN3→partner) and Y-score (partner→SPIN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMEFS →+0.886+0.588<.001<.00132
GBMBCHE →+1.463+0.585<.001<.00132
UCECAKT3 →+0.619+0.341.001<.00132
UCECCNRIP1 →+0.690+0.370.001<.00132
GBMMED13L →+0.392+0.553<.001<.00132
GBMLRCH2 →+0.613+0.485<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,592 associations by consensus.

Exploration