Across TCGA patient cohorts, SPIN2B mutation is significantly associated with the RNA expression of many other genes, with 45 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SPIN2B-associated genes across cancer lineages are RPS29P32, RNU6-572P, and FSCN3. Each is linked with SPIN2B in more than 1 cancer types. Because this analysis shows association rather than direction, both SPIN2B-to-partner and partner-to-SPIN2B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPIN2B→partner) and Y-score (partner→SPIN2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RPS29P32 →	+0.627	+3.014	<.001	.004	3	1
COAD	RNU6-572P →	+0.442	+7.741	<.001	.009	3	1
UCEC	FSCN3 →	+0.209	+3.363	<.001	.007	3	1
UCEC	GNB3 →	+0.803	+3.223	<.001	.009	3	1
UCEC	TBR1 →	+0.634	+2.722	<.001	.007	3	1
LUAD	RNU6-207P →	+0.543	+5.343	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 45 associations by consensus.

Exploration

SPIN2B survival (RNA) · tumor vs normal (RNA) · all SPIN2B data types