SPDYE9

Across TCGA patient cohorts, SPDYE9 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,195 significant associations in total. ESCA shows the largest number of these associations.

The most reproducible SPDYE9-associated GO terms across cancer lineages are Positive regulation of neurogenesis, Regulation of insulin secretion, and Positive regulation of DNA metabolic process. Each is linked with SPDYE9 in more than 6 cancer types. Because this analysis shows association rather than direction, both SPDYE9-to-partner and partner-to-SPDYE9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of neurogenesis grouped by SPDYE9-low versus SPDYE9-high in LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPDYE9→partner) and Y-score (partner→SPDYE9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	Positive regulation of neurogenesis →	+0.048	+0.002	<.001	<.001	2	7
LUSC	Regulation of insulin secretion →	+0.034	+0.002	<.001	<.001	3	6
ESCA	Positive regulation of DNA metabolic process →	+0.062	+0.009	<.001	<.001	3	6
ESCA	Positive regulation of binding →	+0.060	+0.012	<.001	<.001	3	6
STAD	Protein targeting to vacuole →	+0.063	+0.007	<.001	<.001	3	6
STAD	Vacuolar transport →	+0.060	+0.007	<.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,195 associations by consensus.

Positive regulation of neurogenesis by SPDYE9 expression — LUSC

Explore this box plot interactively →