SPDYE8

RNA expression — cross-omics
Cross-omicsRNA → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SPDYE8 RNA expression is significantly associated with the RNA expression of many other genes, with 117 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible SPDYE8-associated genes across cancer lineages are MIR6856, MIR6894, and MIR6726. Each is linked with SPDYE8 in more than 1 cancer types. Because this analysis shows association rather than direction, both SPDYE8-to-partner and partner-to-SPDYE8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPDYE8 versus MIR6856 in SKCM, with a Pearson correlation of 0.21.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPDYE8→partner) and Y-score (partner→SPDYE8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMMIR6856 →+0.537+0.002<.001<.00132
PRADMIR6894 →+0.530+0.003<.001<.00132
PRADMIR6726 →+0.538+0.013<.001<.00132
HNSCMIR6846 →+0.575+0.019<.001<.00132
LUADMIR6893 →+0.653+0.001<.001.00332
PRADRNA5SP131 →+0.604+0.002<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 117 associations by consensus.

SPDYE8 vs MIR6856 — SKCM

Per-sample scatter of SPDYE8 vs MIR6856 in SKCM (Pearson r = 0.21).

Explore this scatter interactively →

Exploration