SPDYE7P

Across TCGA patient cohorts, SPDYE7P mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SPDYE7P-associated genes across cancer lineages are CD4+ naive T-cells, Endothelial cells, and lymphatic Endothelial cells. Each is linked with SPDYE7P in more than 1 cancer types. Because this analysis shows association rather than direction, both SPDYE7P-to-partner and partner-to-SPDYE7P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD4+ naive T-cells grouped by SPDYE7P-low versus SPDYE7P-high in OV.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPDYE7P→partner) and Y-score (partner→SPDYE7P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CD4+ naive T-cells →	+0.019	+6.197	<.001	.026	3	1
UCEC	Endothelial cells →	-0.041	-3.161	.027	.019	3	1
UCEC	lymphatic Endothelial cells →	-0.026	-3.290	.025	.010	3	1
UCEC	Myocytes →	+0.031	+2.883	.046	.032	3	1
UCEC	Erythrocytes →	+0.028	+2.459	.018	.020	1	2

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

CD4+ naive T-cells by SPDYE7P expression — OV

Explore this box plot interactively →