SPDYE7P

Across TCGA pan-cancer cohorts, SPDYE7P RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of SPDYE7P’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where SPDYE7P RNA is repressed in tumor relative to normal tissue. In most cancer types SPDYE7P is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

KICH and LUSC are the cancer types where SPDYE7P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SPDYE7P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	All	−0.054	.001	3	view →
LUSC	Male	III,IV	+0.112	.018	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

SPDYE7P–KICH

Open the KICH breakdown →