SPDYE22P

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SPDYE22P RNA expression is significantly associated with the protein abundance of many other proteins, with 12,995 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SPDYE22P-associated proteins across cancer lineages are RIF1_S782, NCAPG_S674, and RANBP2_S3207. Each is linked with SPDYE22P in more than 5 cancer types. Because this analysis shows association rather than direction, both SPDYE22P-to-partner and partner-to-SPDYE22P results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPDYE22P versus RIF1_S782 in LSCC, with a Pearson correlation of 0.58.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPDYE22P→partner) and Y-score (partner→SPDYE22P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCRIF1_S782 →+0.739+0.410<.001<.00136
LUADNCAPG_S674 →+1.141+0.308<.001.00536
LUADRANBP2_S3207 →+1.017+0.367<.001<.00135
LUADRRM2 →+0.760+0.281<.001<.00135
UCECSMC2 →+0.718+1.042<.001<.00135
LSCCMPHOSPH10 →+0.429+0.456<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 12,995 associations by consensus.

SPDYE22P vs RIF1_S782 — LSCC

Per-sample scatter of SPDYE22P vs RIF1_S782 in LSCC (Pearson r = 0.58).

Explore this scatter interactively →

Exploration