SPDYE22P

Across TCGA patient cohorts, SPDYE22P RNA expression is significantly associated with the go_rna of many other GO terms, with 6,688 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SPDYE22P-associated GO terms across cancer lineages are Negative regulation of chromosome organization, Regulation of DNA-directed DNA polymerase activity, and Regulation of cytokinesis. Each is linked with SPDYE22P in more than 18 cancer types. Because this analysis shows association rather than direction, both SPDYE22P-to-partner and partner-to-SPDYE22P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of chromosome organization grouped by SPDYE22P-low versus SPDYE22P-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPDYE22P→partner) and Y-score (partner→SPDYE22P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of chromosome organization →	+0.079	+0.403	<.001	<.001	3	19
STAD	Regulation of DNA-directed DNA polymerase activity →	+0.073	+0.330	<.001	<.001	3	18
STAD	Regulation of cytokinesis →	+0.068	+0.366	<.001	<.001	3	18
STAD	Negative regulation of mitotic cell cycle →	+0.070	+0.411	<.001	<.001	3	18
STAD	Positive regulation of mitotic cell cycle →	+0.065	+0.390	<.001	<.001	3	18
STAD	Metaphase chromosome alignment →	+0.086	+0.361	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,688 associations by consensus.

Negative regulation of chromosome organization by SPDYE22P expression — STAD

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