SPDYE10P

Across TCGA patient cohorts, SPDYE10P RNA expression is significantly associated with the protein abundance of many other proteins, with 9,139 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SPDYE10P-associated proteins across cancer lineages are MBD3, NONO, and PAFAH1B3. Each is linked with SPDYE10P in more than 3 cancer types. Because this analysis shows association rather than direction, both SPDYE10P-to-partner and partner-to-SPDYE10P results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPDYE10P versus MBD3 in LSCC, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPDYE10P→partner) and Y-score (partner→SPDYE10P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MBD3 →	+0.496	+0.136	.001	.001	3	4
HNSC	NONO →	+0.150	+0.133	<.001	.005	3	3
HNSC	PAFAH1B3 →	+0.336	+0.099	<.001	.006	3	3
LSCC	PDS5B →	+0.268	+0.159	<.001	<.001	3	3
GBM	UNC13D →	-0.388	-0.169	<.001	.002	3	3
HNSC	ZFR →	+0.282	+0.217	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,139 associations by consensus.

SPDYE10P vs MBD3 — LSCC

Explore this scatter interactively →