SPDYE10P

Across TCGA pan-cancer cohorts, SPDYE10P RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of SPDYE10P’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where SPDYE10P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SPDYE10P is over-expressed in tumor.

LUSC, COAD, and KIRC are the cancer types where SPDYE10P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SPDYE10P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	All	+0.015	.002	3	view →
COAD	All	All	+0.006	.031	3	view →
KIRC	Male	IV	+0.008	.031	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

SPDYE10P–LUSC

Open the LUSC breakdown →