SPATA48

Across TCGA cell cohorts, SPATA48 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,542 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SPATA48-associated GO terms across cancer lineages are tRNA surveillance, Glutamatergic neuron differentiation, and Glycolipid catabolic process. Each is linked with SPATA48 in more than 2 cancer types. Because this analysis shows association rather than direction, both SPATA48-to-partner and partner-to-SPATA48 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA surveillance grouped by SPATA48-low versus SPATA48-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA48→partner) and Y-score (partner→SPATA48) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	tRNA surveillance →	+0.085	+0.649	<.001	<.001	3	3
BLOOD_Lymphoma	Glutamatergic neuron differentiation →	+1.467	+0.581	<.001	<.001	3	3
BLOOD_Lymphoma	Glycolipid catabolic process →	-0.100	-0.641	<.001	<.001	3	3
BLOOD_Lymphoma	Oncostatin-M-mediated signaling pathway →	-0.151	-0.533	<.001	.009	3	3
BLOOD_Lymphoma	Inflammatory cell apoptotic process →	-0.125	-0.626	.001	.001	3	3
BLOOD_Lymphoma	Macrophage apoptotic process →	-0.099	-0.509	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,542 associations by consensus.

tRNA surveillance by SPATA48 expression — BLOOD_Lymphoma

Explore this box plot interactively →