SPATA2L

Across TCGA cell cohorts, SPATA2L RNA expression is significantly associated with the go_rna of many other GO terms, with 3,922 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible SPATA2L-associated GO terms across cancer lineages are Vesicle uncoating, Peptidyl-methionine modification, and Transcription pausing by RNA polymerase II. Each is linked with SPATA2L in more than 15 cancer types. Because this analysis shows association rather than direction, both SPATA2L-to-partner and partner-to-SPATA2L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vesicle uncoating grouped by SPATA2L-low versus SPATA2L-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA2L→partner) and Y-score (partner→SPATA2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Vesicle uncoating →	+0.149	+1.031	<.001	<.001	3	16
LIVER	Peptidyl-methionine modification →	+0.240	+0.896	.007	.006	3	14
BONE	Transcription pausing by RNA polymerase II →	+0.202	+0.960	<.001	.001	3	12
UPPER_AERODIGESTIVE_TRACT	Regulation of autophagosome maturation →	+0.086	+0.698	.009	.009	3	11
SKIN	Regulation of protein sumoylation →	+0.104	+0.727	<.001	<.001	3	11
BONE	mRNA alternative polyadenylation →	+0.117	+1.062	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,922 associations by consensus.

Vesicle uncoating by SPATA2L expression — BONE

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