Across TCGA patient cohorts, SPATA12 mutation is significantly associated with the RNA expression of many other genes, with 166 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SPATA12-associated genes across cancer lineages are VTRNA2-2P, LINC00934, and MIR7702. Each is linked with SPATA12 in more than 1 cancer types. Because this analysis shows association rather than direction, both SPATA12-to-partner and partner-to-SPATA12 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA12→partner) and Y-score (partner→SPATA12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	VTRNA2-2P →	+0.455	+2.789	.002	.004	3	2
UCEC	LINC00934 →	+0.138	+2.720	<.001	.004	3	2
UCEC	MIR7702 →	+0.373	+5.060	<.001	.001	3	1
UCEC	MIR8055 →	+0.615	+2.544	.007	.007	3	1
CESC	MRPS10P1 →	+1.056	+4.409	<.001	.006	3	1
CESC	RNU7-173P →	+0.417	+4.969	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 166 associations by consensus.

Exploration

SPATA12 survival (RNA) · tumor vs normal (RNA) · all SPATA12 data types