SPART

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SPART RNA expression is significantly associated with the protein abundance of many other proteins, with 11,019 significant associations in total. COAD shows the largest number of these associations.

The most reproducible SPART-associated proteins across cancer lineages are ESD, TOMM70, and C1orf198. Each is linked with SPART in more than 4 cancer types. Because this analysis shows association rather than direction, both SPART-to-partner and partner-to-SPART results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPART versus ESD in GBM, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPART→partner) and Y-score (partner→SPART) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMESD →+0.347+0.467<.001<.00135
COADTOMM70 →-0.297-0.755<.001<.00134
COADC1orf198 →+0.413+0.915<.001<.00134
LSCCCACNA2D1 →+0.574+0.654<.001.00134
PDACCRK →+0.232+0.402<.001<.00134
CCRCCARHGEF7 →+0.263+0.391<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,019 associations by consensus.

SPART vs ESD — GBM

Per-sample scatter of SPART vs ESD in GBM (Pearson r = 0.38).

Explore this scatter interactively →

Exploration